COVID-19 Research at CSU
While the rest of the world moved to quickly develop a vaccine for COVID-19, teams of undergraduate and graduate students and four members of CSU’s Center for Gene Regulation in Health and Disease (GRHD) joined the effort.
“[COVID-19] is one new research area where GRHD researchers are making contributions, locally and nationally, to addressing this urgent problem,”
— Meredith Bond, Ph.D., dean of the College of Sciences and Health Professions
Working Toward New Medications
Under a microscope, the COVID-19 virus presents as a ball with spikes containing an “S-protein” that latches to receptors on healthy cells and makes way for the virus to enter the body. Dr. Barsanjit Mazumder’s lab discovered that S-protein binding to its receptor on these cells triggers unique signaling events within cells. Understanding the impact of these signaling events may help develop medications that prevent the virus from replicating inside cells.
Working to Combat Inflammation
High COVID-19 fatality rates are largely due to severe inflammation leading to respiratory distress and multiple organ failure. Dr. Bin Su’s lab sought to develop newer, more effective anti-inflammatory drugs that also prevent COVID-19 from spreading to other cells.
Feline Versus Human Coronavirus
Taking a unique approach, Dr. Anthony Berdis’s lab studied feline coronavirus, which does not cause the disease in humans. Because of its similarities to COVID-19, Berdis’s team hope their research will help reveal more about COVID-19’s properties and how it is transferred among humans.
Working Toward a Better Vaccine
In collaboration with the Food and Drug Administration, GRHD Director Dr. Anton Komar’s lab analyzed the virus’ RNA genes to develop approaches for a more effective vaccine design.
Also in this Issue...
Alumna Carrie Kidd (BA '17) sat in an airport in Wuhan, China, during an eight-hour layover on the night of December 30, 2019. As she waited for her next flight, she scrolled through Chinese news sources on her phone. Suddenly, she spotted a headline with Wuhan in the title. Read more >>
Elizabeth Bonham (JD ’15) staff attorney at the American Civil Liberties Union (ACLU) of Ohio in Cleveland, successfully fought for the release of 21 people held by immigration authorities in four Ohio jails as COVID-19 cases spiked at the facilities. Read more >>