
In a chemical engineering laboratory in the heart of Fenn Hall, a team of mathematics and engineering students and faculty begin an expirement that could enhance food safety.
As one person counts down on a stop watch to zero, the team springs into action. As the lettuce drops into a sanitizer bath, red leaf lettuce, contaminated with bacteria, is added, and various samples of the solution are taken to test pH levels, chlorine content and other values. The lettuce is mixed and washed quickly and then removed so more samples can be taken, as the next batch of iceberg hits the conveyor belt.
The elaborate operation is a key component of a groundbreaking research project that is designed to change the way we ensure our food is safe to eat.
The Centers for Disease Control and Prevention estimates that each year food-borne diseases lead to over 128,000 hospitalizations and roughly 3,000 deaths. Many of these illnesses can be traced to the presence of pathogens such as E. coli, Salmonella, and Listeria in fresh produce. Although interventional practices, including highly engineered and monitored washing systems, have been developed to limit public exposure to these pathogens, mortality and illness rates remain stubbornly high.
A multi-disciplinary CSU team has been awarded a three-year grant from the U.S. Department of Agriculture to address this significant public health concern. The team is developing new mathematical models designed to better assess how these pathogens spread through the food supply, and ultimately create better controls to reduce contamination.
“Ironically, the produce washing process has been identified as one of the key points of pathogen transfer in the food supply chain as contaminated produce mixes with uncontaminated food and pathogens ‘escape’ without being completely removed from all items,” says Partha Srinivasan, associate professor of mathematics and principal investigator on the project. “Our team is analyzing the chemical process to better understand how pathogen transfer occurs, while also creating better predictive models for how the entire process impacts food safety.”
Previous models designed to assess how this contamination happens have only taken a “snapshot in time” instead of modeling the entire wash system and all of its inputs, including food intake and outtake, material handling, sanitization and rinsing. This has made predictive analysis difficult at best.
The CSU team, which also includes Dan Munther, associate professor of mathematics, and Chandra Kothapalli, associate professor of chemical engineering, has addressed this by creating a fully operational produce washing system in a laboratory environment that can be controlled, tested and modified based on experimental data collected.
“Currently, we are testing whether or not pathogens present on the red leaf lettuce transfer to the ‘clean’ iceberg lettuce during sanitization,” Dr. Kothapalli adds. “We are also assessing whether changes in certain values, such as the chlorine levels of the sanitization solution, impact pathogen transfer. The data collected will enable us to develop a predictive algorithm for pathogen cross-contamination and chemical analysis of sanitizer performance.”
The team received funding from the Center for Produce Safety and is working with several produce companies to analyze data collected from large, commercial washing systems so they can compare this analysis with laboratory results.

According to the College & University Food Bank Alliance, 36 percent of college students experience food insecurity while nine percent are homeless.

From Ukrainian immigrant to celebrated chef, Natasha Pogrebinsky (BA ’05) turned passion into purpose — opening acclaimed restaurants and sharing her heritage through food and national TV features.

Drew Anderson (BBA ’09) turned his love for homemade sauerkraut into Cleveland Kraut, sold in 3,500+ stores with inventive flavors and national acclaim — proving fermentation can be bold and local.

Sam McNulty (BA ’97) launched his hospitality career at CSU and now runs top Ohio City bars and Market Garden Brewery. He’s also redeveloping Duck Island, connecting Cleveland neighborhoods.

Charlotte Sine graduated from Fenn College in 1958 with a bachelor’s degree in English. That degree served her well during a 46-year career in various editorial positions at Meister Media Worldwide.

President Harlan M. Sands marks his first year, spotlighting CSU’s student-centered achievements: Say Yes scholarships, new partnerships, global outreach, and seven strategic priorities forward together.

A 58‑ft mural by Gary and Laura Dumm now graces CSU’s Michael Schwartz Library, celebrating local landmarks and history, funded by community and tied to Cleveland Memory Project.

Cleveland State has once again been selected by The Wall Street Journal as one of the best universities in the United States.

The Cleveland-Marshall Law Hall of Fame was established in 2017 to honor alumni, faculty, staff, friends and community leaders who have contributed to the success and prestige of the law school.

CSU is part of a statewide partnership, led by College Now Greater Cleveland, selected to join Degrees When Due. This national initiative seeks to assist students who have some college credits to complete their degrees.

Seven new initiatives, including a Forward Together Innovation Challenge, were announced as part of President Harlan Sands’ first State of the University address.
Three highly regarded, results-driven individuals have joined the University’s leadership team.

Cleveland State University has created a series of innovative partnerships with local community colleges which are designed to create a comprehensive, assistive pathway for students to make the easy transition to Cleveland State.

In early 2019, Cleveland became the fourth Say Yes to Education chapter in the nation, thereby making college free for virtually all Cleveland Metropolitan School District (CMSD) graduates.

CSU partnered with the Seven Hills Recreation Center to improve sensory processing and socialization for children with special needs through a pediatric aquatic therapy program.

CSU’s faculty and staff are second to none! Each year, Distinguished Faculty and Staff Awards honor individuals who bring distinction to the University and support student success through their day-to-day efforts.

CSU researchers tackle big challenges —f rom AI-driven fertility analysis and trauma-informed youth programs to brain aneurysm prevention using nanoparticles — fueling innovation across disciplines.

Alumna Virginia McFrederick loved libraries. And because she included CSU in her estate plan, the Michael Schwartz Library is now home to the Virginia McFrederick Group Study Center.

Cleveland State University will expand innovative education, research and experiential learning in real estate and property management, thanks to a transformative $1.2 million gift from the NRP Group and the Millennia Companies.

Gina Vernaci had spent nearly four decades as a theater manager and administrator and was in the middle of a highly successful tenure at Cleveland’s Playhouse Square when a lunchtime walk changed her educational and professional path.

CSU is Viking Strong with a worldwide network of 130,000-plus alumni. Each year, a select group who bring distinction to the University through their career achievements, service and engagement are honored with Distinguished Alumni Awards.

Alumnus sees medicine as a vehicle for improving the community

From behind-the-scenes visits to well-known (and little-known) Cleveland sites to world tours, the CSU Alumni Association’s calendar of events has something for everyone.

A people-powered parade, golden apples, a harvest picnic, reunions, dedications, awards . . . Homecoming 2019 was packed with activities that brought alumni and their families back to campus.

According to the College & University Food Bank Alliance, 36 percent of college students experience food insecurity while nine percent are homeless.

Drew Anderson (BBA ’09) turned his love for homemade sauerkraut into Cleveland Kraut, sold in 3,500+ stores with inventive flavors and national acclaim — proving fermentation can be bold and local.

Charlotte Sine graduated from Fenn College in 1958 with a bachelor’s degree in English. That degree served her well during a 46-year career in various editorial positions at Meister Media Worldwide.

A 58‑ft mural by Gary and Laura Dumm now graces CSU’s Michael Schwartz Library, celebrating local landmarks and history, funded by community and tied to Cleveland Memory Project.

The Cleveland-Marshall Law Hall of Fame was established in 2017 to honor alumni, faculty, staff, friends and community leaders who have contributed to the success and prestige of the law school.

Seven new initiatives, including a Forward Together Innovation Challenge, were announced as part of President Harlan Sands’ first State of the University address.

Cleveland State University has created a series of innovative partnerships with local community colleges which are designed to create a comprehensive, assistive pathway for students to make the easy transition to Cleveland State.

CSU partnered with the Seven Hills Recreation Center to improve sensory processing and socialization for children with special needs through a pediatric aquatic therapy program.

CSU researchers tackle big challenges —f rom AI-driven fertility analysis and trauma-informed youth programs to brain aneurysm prevention using nanoparticles — fueling innovation across disciplines.

Cleveland State University will expand innovative education, research and experiential learning in real estate and property management, thanks to a transformative $1.2 million gift from the NRP Group and the Millennia Companies.

CSU is Viking Strong with a worldwide network of 130,000-plus alumni. Each year, a select group who bring distinction to the University through their career achievements, service and engagement are honored with Distinguished Alumni Awards.

From behind-the-scenes visits to well-known (and little-known) Cleveland sites to world tours, the CSU Alumni Association’s calendar of events has something for everyone.

From Ukrainian immigrant to celebrated chef, Natasha Pogrebinsky (BA ’05) turned passion into purpose — opening acclaimed restaurants and sharing her heritage through food and national TV features.

Sam McNulty (BA ’97) launched his hospitality career at CSU and now runs top Ohio City bars and Market Garden Brewery. He’s also redeveloping Duck Island, connecting Cleveland neighborhoods.

President Harlan M. Sands marks his first year, spotlighting CSU’s student-centered achievements: Say Yes scholarships, new partnerships, global outreach, and seven strategic priorities forward together.

Cleveland State has once again been selected by The Wall Street Journal as one of the best universities in the United States.

CSU is part of a statewide partnership, led by College Now Greater Cleveland, selected to join Degrees When Due. This national initiative seeks to assist students who have some college credits to complete their degrees.
Three highly regarded, results-driven individuals have joined the University’s leadership team.

In early 2019, Cleveland became the fourth Say Yes to Education chapter in the nation, thereby making college free for virtually all Cleveland Metropolitan School District (CMSD) graduates.

CSU’s faculty and staff are second to none! Each year, Distinguished Faculty and Staff Awards honor individuals who bring distinction to the University and support student success through their day-to-day efforts.

Alumna Virginia McFrederick loved libraries. And because she included CSU in her estate plan, the Michael Schwartz Library is now home to the Virginia McFrederick Group Study Center.

Gina Vernaci had spent nearly four decades as a theater manager and administrator and was in the middle of a highly successful tenure at Cleveland’s Playhouse Square when a lunchtime walk changed her educational and professional path.

Alumnus sees medicine as a vehicle for improving the community

A people-powered parade, golden apples, a harvest picnic, reunions, dedications, awards . . . Homecoming 2019 was packed with activities that brought alumni and their families back to campus.

According to the College & University Food Bank Alliance, 36 percent of college students experience food insecurity while nine percent are homeless.

Sam McNulty (BA ’97) launched his hospitality career at CSU and now runs top Ohio City bars and Market Garden Brewery. He’s also redeveloping Duck Island, connecting Cleveland neighborhoods.

A 58‑ft mural by Gary and Laura Dumm now graces CSU’s Michael Schwartz Library, celebrating local landmarks and history, funded by community and tied to Cleveland Memory Project.

CSU is part of a statewide partnership, led by College Now Greater Cleveland, selected to join Degrees When Due. This national initiative seeks to assist students who have some college credits to complete their degrees.

Cleveland State University has created a series of innovative partnerships with local community colleges which are designed to create a comprehensive, assistive pathway for students to make the easy transition to Cleveland State.

CSU’s faculty and staff are second to none! Each year, Distinguished Faculty and Staff Awards honor individuals who bring distinction to the University and support student success through their day-to-day efforts.

Cleveland State University will expand innovative education, research and experiential learning in real estate and property management, thanks to a transformative $1.2 million gift from the NRP Group and the Millennia Companies.

Alumnus sees medicine as a vehicle for improving the community

From Ukrainian immigrant to celebrated chef, Natasha Pogrebinsky (BA ’05) turned passion into purpose — opening acclaimed restaurants and sharing her heritage through food and national TV features.

Charlotte Sine graduated from Fenn College in 1958 with a bachelor’s degree in English. That degree served her well during a 46-year career in various editorial positions at Meister Media Worldwide.

Cleveland State has once again been selected by The Wall Street Journal as one of the best universities in the United States.

Seven new initiatives, including a Forward Together Innovation Challenge, were announced as part of President Harlan Sands’ first State of the University address.

In early 2019, Cleveland became the fourth Say Yes to Education chapter in the nation, thereby making college free for virtually all Cleveland Metropolitan School District (CMSD) graduates.

CSU researchers tackle big challenges —f rom AI-driven fertility analysis and trauma-informed youth programs to brain aneurysm prevention using nanoparticles — fueling innovation across disciplines.

Gina Vernaci had spent nearly four decades as a theater manager and administrator and was in the middle of a highly successful tenure at Cleveland’s Playhouse Square when a lunchtime walk changed her educational and professional path.

From behind-the-scenes visits to well-known (and little-known) Cleveland sites to world tours, the CSU Alumni Association’s calendar of events has something for everyone.

Drew Anderson (BBA ’09) turned his love for homemade sauerkraut into Cleveland Kraut, sold in 3,500+ stores with inventive flavors and national acclaim — proving fermentation can be bold and local.

President Harlan M. Sands marks his first year, spotlighting CSU’s student-centered achievements: Say Yes scholarships, new partnerships, global outreach, and seven strategic priorities forward together.

The Cleveland-Marshall Law Hall of Fame was established in 2017 to honor alumni, faculty, staff, friends and community leaders who have contributed to the success and prestige of the law school.
Three highly regarded, results-driven individuals have joined the University’s leadership team.

CSU partnered with the Seven Hills Recreation Center to improve sensory processing and socialization for children with special needs through a pediatric aquatic therapy program.

Alumna Virginia McFrederick loved libraries. And because she included CSU in her estate plan, the Michael Schwartz Library is now home to the Virginia McFrederick Group Study Center.

CSU is Viking Strong with a worldwide network of 130,000-plus alumni. Each year, a select group who bring distinction to the University through their career achievements, service and engagement are honored with Distinguished Alumni Awards.

A people-powered parade, golden apples, a harvest picnic, reunions, dedications, awards . . . Homecoming 2019 was packed with activities that brought alumni and their families back to campus.